Selected Publications
Case Study 3: A 58-Year-Old Woman Referred for Evaluation of Suspected Alzheimer Dementia
Maneval J, Woods JK, Feany MB, Miller MB, Silbersweig DA, Gale SA, Daffner KR, McGinnis SM. J Neuropsychiatry Clin Neurosci. 2022.
Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders
Kim J, Huang AY, Johnson SL, Lai J, Isacco L, Jeffries AM, Miller MB, Lodato MA, Walsh CA, Lee EA. Nature Communications. 2022.
Choudhury S, Huang AY, Kim J, Zhou Z, Morillo K, Maury EA, Tsai JW, Miller MB, Lodato MA, Araten S, Hilal N, Lee EA, Chen MH, Walsh CA. Nature Aging. 2022.
Case Study 2: A 60-Year-Old Man With Progressive Defecits in Language Output
Thurin K, Patel V, Perez DL, Dickerson BC, Hochberg D, Quimby M, Miller MB, Feany M, Silbersweig D, McGinnis SM, Daffner KR, Gale SA. J Neuropsychiatry Clin Neurosci. 2022.
Luquette LJ*, Miller MB*, Zhou Z*, Bohrson CL, Zhao Y, Jin H, Gulhan D, Ganz J, Bizzotto S, Kirkham SL, Hochepied T, Libert C, Galor A, Kim J, Lodato MA, Garaycoechea JI, Gawad C, West J, Walsh CA, Park PJ. Nature Genetics. 2022.
Somatic genomic changes in single Alzheimer's disease neurons
Miller MB*, Huang AY*, Kim J, Zhou Z, Kirkham SL, Maury EA, Ziegenfuss JS, Reed HC, Neil JE, Rento L, Ryu SC, Ma CC, Luquette LJ, Ames HM, Oakley DH, Frosch MP, Hyman BT, Lodato MA, Lee EA, Walsh CA. Nature. 2022.
Stern AM, Liu L, Jin S, Liu W, Meunier AL, Ericsson M, Miller MB, Batson M, Sun T, Kathuria S, Reczek D, Pradier L, Selkoe DJ. Brain. 2022.
Case Study 1: A 55-Year-Old Woman With Progressive Cognitive, Perceptual, and Motor Impairments
McGinnis SM, Stern AM, Woods JK, Torre M, Feany MB, Miller MB, Silbersweig DA, Gale SA, Daffner KR. J Neuropsychiatry Clin Neurosci. 2022.
Brain Somatic Mutation in Aging and Alzheimer's Disease
Miller MB, Reed HC, Walsh CA. Annu Rev Genomics Hum Genet. 2021.
MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations
Doan RN, Miller MB, Kim SN, Rodin RE, Ganz J, Bizzotto S, Morillo KS, Huang AY, Digumarthy R, Zemmel Z, Walsh CA. BMC Med Genomics. 2021.
Shah K, Folpe AL, Miller M, Morgan JA, Raut CP, Doyle LA. Histopathology. 2021.
APP gene copy number changes reflect exogenous contamination
Kim J, Zhao B, Huang AY, Miller MB, Lodato MA, Walsh CA, Lee EA. Nature. 2020.
Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma
Cagney DN, Miller MB, Dubuc A, Delalle I, Ligon AH, Chukwueke U, Al-Mefty O, Aizer A, Ligon K, Wen P. Cureus. 2019.
Spindle cell oncocytoma of the pituitary gland
Giantini Larsen AM, Cote DJ, Zaidi HA, Bi WL, Schmitt PJ, Iorgulescu JB, Miller MB, Smith TR, Lopes MB, Jane JA, Laws ER. J Neurosurg. 2018.
Spinal Cord as a Complication of "Stem-Cell Tourism"
Berkowitz AL*, Miller MB*, Mir SA, Cagney D, Chavakula V, Guleria I, Aizer A, Ligon KL, Chi JH. Glioproliferative Lesion of the N Engl J Med. 2016.
MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma
Miller MB*, Bi WL*, Ramkissoon LA, Kang YJ, Abedalthagafi M, Knoff DS, Agarwalla PK, Wen PY, Reardon DA, Alexander BM, Laws ER Jr, Dunn IF, Beroukhim R, Ligon KL, Ramkissoon SH. Oncotarget. 2016.
Status epilepticus caused by cerebral amyloid angiopathy-related inflammation
Tolchin B, Fantaneanu T, Miller M, Helgager J, Lee JW. Epilepsy Behav Case Rep. 2016.
Farmakiotis D, Liakos A, Miller MB, Krane JF, Baden LR, Hammond SP. J Clin Med Res. 2016.
Multicentric Low-Grade Gliomas
Sridharan V, Urbanski LM, Bi WL, Thistle K, Miller MB, Ramkissoon S, Reardon DA, Dunn IF. World Neurosurg. 2015.
Noble GP, Wang DW, Walsh DJ, Barone JR, Miller MB, Nishina KA, Li S, Supattapone S. PLoS Pathog. 2015.
Regulatory T cells are not a strong predictor of survival for patients with glioblastoma
Thomas AA, Fisher JL, Rahme GJ, Hampton TH, Baron U, Olek S, Schwachula T, Rhodes CH, Gui J, Tafe LJ, Tsongalis GJ, Lefferts JA, Wishart H, Kleen J, Miller M, Whipple CA, de Abreu FB, Ernstoff MS, Fadul CE. Neuro Oncol. 2015.
Requirements for mutant and wild-type prion protein misfolding in vitro
Noble GP, Walsh DJ, Miller MB, Jackson WS, Supattapone S. Biochemistry. 2015.
Cofactor molecules induce structural transformation during infectious prion formation
Miller MB, Wang DW, Wang F, Noble GP, Ma J, Woods VL Jr, Li S, Supattapone S. Structure. 2013.
Praitis V, Simske J, Kniss S, Mandt R, Imlay L, Feddersen C, Miller MB, Mushi J, Liszewski W, Weinstein R, Chakravorty A, Ha DG, Schacht Farrell A, Sullivan-Wilson A, Stock T. PLoS Genet. 2013.
Cofactor Involvement in Prion Propagation
Supattapone S, Miller M. In: Zou WQ, Gambetti P, editors. Prions and Diseases: Physiology and Pathophysiology New York: Springer; 2013. Chapter 7; p.93-105.
Turnbaugh JA, Unterberger U, Saá P, Massignan T, Fluharty BR, Bowman FP, Miller MB, Supattapone S, Biasini E, Harris DA. J Neurosci. 2012.
Dissociation of infectivity from seeding ability in prions with alternate docking mechanism
Miller MB, Geoghegan JC, Supattapone S. PLoS Pathog. 2011.
Superparamagnetic nanoparticle capture of prions for amplification
Miller MB, Supattapone S. J Virol. 2011 Mar;85(6):2813-7. doi: 10.1128/JVI.02451-10. Epub 2011.
Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor
Geoghegan JC, Miller MB, Kwak AH, Harris BT, Supattapone S. PLoS Pathog. 2009.